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Joseph Gordon-Levitt
Adam Lerner
Seth Rogen
Kyle Hirons
Anna Kendrick
Katherine McKay
Bryce Dallas Howard
Rachael
Anjelica Huston
Diane Lerner
Serge Houde
Richard Lerner
Philip Baker Hall
Alan
Matt Frewer
Mitch
Andrew Airlie
Dr. Ross
Peter Kelamis
Phil
Jessica Parker Kennedy
Jackie
Sugar Lyn Beard
Susan
Donna Yamamoto
Dr. Walderson
Yee Jee Tso
Dr. Lee
Sarah Smyth
Jenny
Daniel Bacon
Dr. Phillips
P. Lynn Johnson
Bernie
Laura Bertram
Claire
Matty Finochio
Ted
Marie Avgeropoulos
Allison
Luisa d'Oliveira
Agabelle Loogenburgen
Veena Sood
Nurse Stewart
Andrea Brooks
Attractive Woman #2
Beatrice King
Pretty Girl
Chilton Crane
Mother on the Bus
Lauren Miller Rogen
Bodie
Jason Vaisvila
Cute Guy with Dreads
Brent Sheppard
Minister
Stephanie Belding
Friendly Nurse
Ryan W. Smith
Joe
William 'Big Sleeps' Stewart
George
Amitai Marmorstein
Young Person on the Bus
Will Reiser
Greg
Christopher De-Schuster
Art Gallery Patron
Adrian Glynn McMorran
Bartender
Karen van Blankenstein
Nurse Scott
Richard C. Burton
Thom the Patient
Susan De West
Bar Girl
Neil Corbett
Hospital Tech
Stephen Colbert
Self (archive footage) (uncredited)
D. C. Douglas
Live Volcano Reporter (voice) (uncredited)
Cameron K. Smith
Chemo Patient (uncredited)
Tom MacNeill
Office Staff (uncredited)