Malignant
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Annabelle Wallis
Madison Mitchell
Maddie Hasson
Sydney Lake
George Young
Detective Kekoa Shaw
Michole Briana White
Detective Regina Moss
Susanna Thompson
Jeanne
Ingrid Bisu
Winnie
Jean Louisa Kelly
Jane Doe
Jake Abel
Derek Mitchell
Jacqueline McKenzie
Dr. Florence Weaver
Christian Clemenson
Dr. Victor Fields
Amir Aboulela
Dr. Gregory
Mercedes Colon
Mendez
Ruben Pla
Officer Rubin
Jon Lee Brody
Officer Lee
Paula Marshall
Beverly Woods
Zoë Bell
Scorpion
Shaunte Lynette Johnson
Beta
Natalia Safran
Nurse Annie
Mike Mendez
Hospital Security Guard #1
Randy Haynie
Hospital Security Guard #2
Cord Walker
Hospital Security Guard #3
Jesus Trujillo
Research Doctor
Lisa Catara
Research Orderly
Danielle Nottingham
News Anchor
Ray Chase
Gabriel (voice)
Marina Mazepa
Gabriel
Mckenna Grace
Young Madison
Madison Wolfe
Young Serena
Andy Bean
Frank
Patricia Velásquez
Nurse Velasquez
Patrick Cox
Mr. Stanley (uncredited)
Gregory Garcia
Seattle Police Officer (uncredited)
Emir García
Mustang Driver (uncredited)
Renee Harbek
Caroline (uncredited)
Janet Hsieh
Nurse J. De Marco (uncredited)
Paul Mabon
Orderly (uncredited)
Gino Montesinos
Seattle Police Officer (uncredited)
Josh Rutgers
Referee (uncredited)
Halston Van Atta
Child Madison (uncredited)
Louise Van Veenendaal
Prisoner (uncredited)
Kalina Vanska
Seattle Police Officer (uncredited)
Christina Veronica
Prisoner (uncredited)
Rachel Winfree
Mrs. Ryerson (uncredited)